Q. A 30-year-old woman develops a urinary tract infection. A urine culture shows the presence of a gram-negative bacillus. Which organism is the most common cause of such infections?
A.Escherichia coli
B.Proteus mirabilis
C.Enterococcus faecalis
D.Klebsiella pneumoniae
Solution
Escherichia coli is the most common cause of urinary tract infections.
Q. A 30-year-old woman is diagnosed with systemic lupus erythematosus (SLE). What type of immune response is primarily involved in this autoimmune disease?
A.Innate immune response
B.Humoral immune response
C.Cell-mediated immune response
D.Complement-mediated response
Solution
SLE is characterized by a humoral immune response, particularly the production of autoantibodies.
Q. A 45-year-old man presents with fever, cough, and chest pain. A chest X-ray shows a cavitary lesion in the right upper lobe. Which microorganism is most likely responsible for this condition?
A.Streptococcus pneumoniae
B.Mycobacterium tuberculosis
C.Klebsiella pneumoniae
D.Legionella pneumophila
Solution
The cavitary lesion in the right upper lobe is characteristic of pulmonary tuberculosis, which is caused by Mycobacterium tuberculosis.
Q. A 50-year-old man presents with fever, night sweats, and weight loss. A biopsy of a lymph node reveals granulomas. Which infectious agent is most likely responsible?
A.Histoplasma capsulatum
B.Mycobacterium tuberculosis
C.Coccidioides immitis
D.Brucella spp.
Solution
Granulomas in the lymph nodes are characteristic of tuberculosis, which is caused by Mycobacterium tuberculosis.
Q. A culture shows a growth of 1,200 colonies after incubation. If the dilution factor was 1:100, what was the original concentration of bacteria in the sample?
A.120,000 CFU/mL
B.12,000 CFU/mL
C.1,200 CFU/mL
D.120 CFU/mL
Solution
To find the original concentration, multiply the number of colonies by the dilution factor: 1,200 colonies * 100 = 120,000 CFU/mL.
Q. A laboratory technician is exposed to a needle stick injury from a patient with hepatitis B. What is the most appropriate post-exposure prophylaxis?
A.Hepatitis B vaccine
B.Hepatitis A vaccine
C.Intravenous immunoglobulin
D.No treatment necessary
Solution
Post-exposure prophylaxis for hepatitis B includes administering the hepatitis B vaccine.
Q. A laboratory test shows that a patient has a viral load of 5,000 copies/mL. If the treatment reduces the viral load by 80%, what is the new viral load?
A.1,000 copies/mL
B.2,000 copies/mL
C.3,000 copies/mL
D.4,000 copies/mL
Solution
An 80% reduction means that 20% of the original viral load remains. 20% of 5,000 copies/mL is 1,000 copies/mL.
Q. A patient is diagnosed with a bacterial infection and is prescribed antibiotics. If the bacteria have a resistance rate of 25%, what is the probability that a randomly selected bacterium is susceptible to the antibiotic?
A.25%
B.50%
C.75%
D.100%
Solution
If 25% of the bacteria are resistant, then 75% are susceptible to the antibiotic.
Q. A patient presents with a sudden onset of high fever, chills, and a petechial rash. Blood cultures reveal Neisseria meningitidis. What is the most effective preventive measure?
A.Antibiotic prophylaxis
B.Meningococcal vaccine
C.Isolation of the patient
D.Intravenous immunoglobulin
Solution
The meningococcal vaccine is the most effective preventive measure against Neisseria meningitidis infection.
Q. A patient presents with severe diarrhea and dehydration. Stool culture reveals the presence of a toxin-producing organism. Which organism is most likely responsible?
A.Escherichia coli
B.Clostridium difficile
C.Salmonella enterica
D.Vibrio cholerae
Solution
Clostridium difficile is known for causing antibiotic-associated diarrhea and produces toxins that lead to severe gastrointestinal symptoms.
Q. A patient with a history of travel to tropical regions presents with fever, jaundice, and abdominal pain. Which virus is most likely responsible for these symptoms?
A.Hepatitis A virus
B.Hepatitis B virus
C.Dengue virus
D.Yellow fever virus
Solution
Yellow fever virus is endemic in tropical regions and can cause fever, jaundice, and abdominal pain.