Vibrio cholerae is the bacterium responsible for cholera, a disease characterized by severe diarrhea and dehydration.
Correct Answer: A — Vibrio cholerae
Q. Which cells are primarily responsible for the production of antibodies?
A.T cells
B.B cells
C.Macrophages
D.Dendritic cells
Solution
B cells are the primary cells responsible for the production of antibodies in response to antigens.
Correct Answer: B — B cells
Q. Which chemical agent is commonly used for high-level disinfection?
A.Ethanol
B.Chlorine
C.Glutaraldehyde
D.Hydrogen peroxide
Solution
Glutaraldehyde is widely used for high-level disinfection of medical equipment.
Correct Answer: C — Glutaraldehyde
Q. Which cytokine is known for its role in promoting the differentiation of T cells?
A.Interleukin-1
B.Interleukin-2
C.Tumor necrosis factor
D.Interferon-gamma
Solution
Interleukin-2 is crucial for the proliferation and differentiation of T cells during the immune response.
Correct Answer: B — Interleukin-2
Q. Which cytokine is primarily involved in the activation of T cells?
A.Interleukin-1
B.Interleukin-2
C.Tumor necrosis factor-alpha
D.Interferon-gamma
Solution
Interleukin-2 is crucial for T cell proliferation and activation, making it a key cytokine in the immune response.
Correct Answer: B — Interleukin-2
Q. Which cytokine is primarily involved in the differentiation of naive T cells into Th1 cells?
A.IL-4
B.IL-12
C.IFN-gamma
D.TGF-beta
Solution
IL-12 is crucial for the differentiation of naive T cells into Th1 cells, which are important for cell-mediated immunity.
Correct Answer: B — IL-12
Q. Which cytokine is primarily responsible for activating macrophages during an immune response?
A.IL-1
B.IL-6
C.IFN-gamma
D.TNF-alpha
Solution
IFN-gamma is the key cytokine that activates macrophages, enhancing their ability to phagocytose pathogens.
Correct Answer: C — IFN-gamma
Q. Which cytokine is primarily responsible for the differentiation of naive T cells into Th1 cells?
A.IL-4
B.IL-12
C.IFN-gamma
D.TNF-alpha
Solution
IL-12 is the key cytokine that promotes the differentiation of naive T cells into Th1 cells, which are important for cell-mediated immunity.
Correct Answer: B — IL-12
Q. Which immune cells are primarily involved in the adaptive immune response?
A.Neutrophils
B.Macrophages
C.B and T lymphocytes
D.Natural killer cells
Solution
B and T lymphocytes are the main components of the adaptive immune response, responsible for specific recognition and memory.
Correct Answer: C — B and T lymphocytes
Q. Which immune cells are primarily involved in the clearance of intracellular pathogens?
A.B cells
B.Cytotoxic T cells
C.Helper T cells
D.Natural killer cells
Solution
Cytotoxic T cells are primarily responsible for recognizing and killing cells infected with intracellular pathogens, such as viruses.
Correct Answer: B — Cytotoxic T cells
Q. Which immune cells are primarily involved in the response to helminth infections?
A.Neutrophils
B.Macrophages
C.Eosinophils
D.B cells
Solution
Eosinophils play a key role in the immune response against helminth infections, as they are involved in the destruction of larger parasites.
Correct Answer: C — Eosinophils
Q. Which immune cells are primarily responsible for the adaptive immune response?
A.Neutrophils
B.Macrophages
C.B and T lymphocytes
D.Natural killer cells
Solution
B and T lymphocytes are the key players in the adaptive immune response, providing specific immunity against pathogens.
Correct Answer: C — B and T lymphocytes
Q. Which immune cells are primarily responsible for the destruction of virus-infected cells?
A.B cells
B.T helper cells
C.Cytotoxic T cells
D.Macrophages
Solution
Cytotoxic T cells are responsible for directly killing virus-infected cells.
Correct Answer: C — Cytotoxic T cells
Q. Which immune response is primarily involved in fighting viral infections?
A.Humoral immunity
B.Cell-mediated immunity
C.Innate immunity
D.Complement system
Solution
Cell-mediated immunity, particularly through cytotoxic T cells, is crucial for targeting and eliminating virus-infected cells.
Correct Answer: B — Cell-mediated immunity
Q. Which immunoglobulin is primarily found in mucosal areas and is important for mucosal immunity?
A.IgG
B.IgA
C.IgM
D.IgE
Solution
IgA is the main immunoglobulin found in mucosal areas, providing protection against pathogens at mucosal surfaces.
Correct Answer: B — IgA
Q. Which immunoglobulin is primarily involved in the allergic response?
A.IgA
B.IgD
C.IgE
D.IgG
Solution
IgE is the immunoglobulin primarily involved in allergic reactions and responses to parasitic infections.
Correct Answer: C — IgE
Q. Which immunoglobulin is the first to be produced in response to an infection?
A.IgA
B.IgG
C.IgM
D.IgE
Solution
IgM is the first immunoglobulin produced in response to an infection, providing an early defense against pathogens.
Correct Answer: C — IgM
Q. Which laboratory test is commonly used to diagnose HIV infection?
A.Complete blood count
B.ELISA test
C.PCR test
D.Culture test
Solution
The ELISA test is commonly used to detect antibodies against HIV, indicating infection.
Correct Answer: B — ELISA test
Q. Which laboratory test is commonly used to diagnose streptococcal pharyngitis?
A.Blood culture
B.Rapid antigen test
C.PCR test
D.Urinalysis
Solution
A rapid antigen test is commonly used to quickly diagnose streptococcal pharyngitis (strep throat).
Correct Answer: B — Rapid antigen test
Q. Which laboratory test is most commonly used to diagnose streptococcal pharyngitis?
A.Blood culture
B.Rapid antigen detection test
C.PCR assay
D.Complete blood count
Solution
The rapid antigen detection test is commonly used to quickly diagnose streptococcal pharyngitis by detecting Group A Streptococcus antigens.
Correct Answer: B — Rapid antigen detection test
Q. Which microorganism is known for causing cholera?
A.Vibrio cholerae
B.Salmonella enterica
C.Clostridium botulinum
D.Listeria monocytogenes
Solution
Vibrio cholerae is the bacterium that causes cholera, a severe diarrheal disease often linked to contaminated water.
Correct Answer: A — Vibrio cholerae
Q. Which microorganism is primarily responsible for causing tuberculosis?
A.Streptococcus pneumoniae
B.Mycobacterium tuberculosis
C.Escherichia coli
D.Staphylococcus aureus
Solution
Mycobacterium tuberculosis is the causative agent of tuberculosis, a serious infectious disease that primarily affects the lungs.
Correct Answer: B — Mycobacterium tuberculosis
Q. Which of the following diseases is caused by a prion?
A.HIV/AIDS
B.Mad Cow Disease
C.Tuberculosis
D.Malaria
Solution
Mad Cow Disease, or Bovine Spongiform Encephalopathy, is caused by prions, which are misfolded proteins that induce abnormal folding of normal proteins.
Correct Answer: B — Mad Cow Disease
Q. Which of the following diseases is caused by a virus?
A.Tuberculosis
B.HIV/AIDS
C.Strep throat
D.Malaria
Solution
HIV/AIDS is caused by the human immunodeficiency virus (HIV), which attacks the immune system.
Correct Answer: B — HIV/AIDS
Q. Which of the following disinfectants is effective against spores?
A.Alcohol
B.Chlorine
C.Hydrogen peroxide
D.Quaternary ammonium compounds
Solution
Hydrogen peroxide is effective against spores, especially at higher concentrations, making it a suitable disinfectant for various applications.
Correct Answer: C — Hydrogen peroxide
Q. Which of the following factors does NOT affect the efficacy of a disinfectant?
A.Concentration of the disinfectant
B.Presence of organic matter
C.Temperature
D.Color of the disinfectant
Solution
The color of the disinfectant does not affect its efficacy; however, concentration, organic matter, and temperature do.
Correct Answer: D — Color of the disinfectant
Q. Which of the following factors does NOT affect the efficacy of disinfectants?
A.Concentration of the disinfectant
B.Contact time
C.Type of microorganism
D.Color of the disinfectant
Solution
The color of the disinfectant does not affect its efficacy; however, concentration, contact time, and type of microorganism do.
Correct Answer: D — Color of the disinfectant
Q. Which of the following factors does NOT affect the efficacy of disinfection?
A.Concentration of the disinfectant
B.Contact time
C.Temperature
D.Color of the disinfectant
Solution
The color of the disinfectant does not affect its efficacy; however, concentration, contact time, and temperature do.
Correct Answer: D — Color of the disinfectant
Q. Which of the following is a characteristic feature of Gram-negative bacteria?
A.Thick peptidoglycan layer
B.Outer membrane containing lipopolysaccharides
C.Staining purple in Gram stain
D.Sensitive to penicillin
Solution
Gram-negative bacteria have an outer membrane that contains lipopolysaccharides, which is a key characteristic distinguishing them from Gram-positive bacteria.
Correct Answer: B — Outer membrane containing lipopolysaccharides
Q. Which of the following is a characteristic of a high-level disinfectant?
A.Effective against all bacteria
B.Effective against spores
C.Requires heat for activation
D.Can be used on skin
Solution
High-level disinfectants are effective against spores, making them suitable for critical items.