Microbiology & Immunology
Q. Which of the following is NOT a method of disinfection?
A.
Ultraviolet light
B.
Autoclaving
C.
Chemical disinfectants
D.
Boiling water
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Solution
Autoclaving is a method of sterilization, not disinfection, as it kills all microorganisms including spores.
Correct Answer: B — Autoclaving
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Q. Which of the following is NOT a method of sterilization?
A.
Filtration
B.
Radiation
C.
Boiling water
D.
Autoclaving
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Solution
Boiling water is not a reliable method of sterilization as it does not kill all spores and certain resistant pathogens.
Correct Answer: C — Boiling water
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Q. Which of the following methods is most effective for sterilizing heat-sensitive instruments?
A.
Autoclaving
B.
Ethylene oxide gas
C.
Dry heat sterilization
D.
Chemical disinfection
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Solution
Ethylene oxide gas is effective for sterilizing heat-sensitive instruments as it can penetrate materials without causing damage.
Correct Answer: B — Ethylene oxide gas
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Q. Which of the following methods is NOT considered a form of sterilization?
A.
Autoclaving
B.
Dry heat sterilization
C.
Chemical disinfection
D.
Filtration
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Solution
Chemical disinfection is a method used to reduce microbial load but does not guarantee the elimination of all microorganisms, thus it is not considered sterilization.
Correct Answer: C — Chemical disinfection
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Q. Which of the following methods is NOT typically used for sterilization?
A.
Autoclaving
B.
Dry heat
C.
Chemical disinfection
D.
Filtration
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Solution
Chemical disinfection is used to reduce microbial load but does not guarantee the elimination of all microorganisms, thus it is not a sterilization method.
Correct Answer: C — Chemical disinfection
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Q. Which of the following microorganisms is known to cause tuberculosis?
A.
Streptococcus pneumoniae
B.
Mycobacterium tuberculosis
C.
Escherichia coli
D.
Staphylococcus aureus
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Solution
Mycobacterium tuberculosis is the causative agent of tuberculosis, a serious infectious disease that primarily affects the lungs.
Correct Answer: B — Mycobacterium tuberculosis
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Q. Which of the following microorganisms is primarily responsible for causing tuberculosis?
A.
Streptococcus pneumoniae
B.
Mycobacterium tuberculosis
C.
Escherichia coli
D.
Staphylococcus aureus
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Solution
Mycobacterium tuberculosis is the causative agent of tuberculosis, a serious infectious disease that primarily affects the lungs.
Correct Answer: B — Mycobacterium tuberculosis
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Q. Which of the following organisms is most resistant to sterilization methods?
A.
Escherichia coli
B.
Streptococcus pneumoniae
C.
Bacillus anthracis spores
D.
HIV
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Solution
Bacillus anthracis spores are highly resistant to sterilization methods, making them a significant concern in sterilization processes.
Correct Answer: C — Bacillus anthracis spores
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Q. Which of the following vaccines is a live attenuated vaccine?
A.
Influenza vaccine
B.
MMR (Measles, Mumps, Rubella) vaccine
C.
Hepatitis B vaccine
D.
Tetanus toxoid vaccine
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Solution
The MMR vaccine contains live attenuated viruses that stimulate an immune response without causing the disease.
Correct Answer: B — MMR (Measles, Mumps, Rubella) vaccine
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Q. Which pathogen is known for causing a severe form of gastroenteritis, particularly in children?
A.
Norovirus
B.
Clostridium difficile
C.
Salmonella enterica
D.
Escherichia coli O157:H7
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Solution
Norovirus is a leading cause of gastroenteritis outbreaks, especially in children, due to its high transmissibility and low infectious dose.
Correct Answer: A — Norovirus
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Q. Which pathogen is known for causing foodborne illness through contaminated poultry?
A.
Salmonella
B.
Listeria
C.
E. coli
D.
Clostridium botulinum
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Solution
Salmonella is a common cause of foodborne illness, often associated with undercooked poultry.
Correct Answer: A — Salmonella
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Q. Which pathogen is known for causing the most severe form of viral gastroenteritis in children?
A.
Rotavirus
B.
Norovirus
C.
Adenovirus
D.
Enterovirus
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Solution
Rotavirus is the leading cause of severe viral gastroenteritis in children, leading to dehydration and hospitalization.
Correct Answer: A — Rotavirus
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Q. Which pathogen is known to cause cholera?
A.
Vibrio cholerae
B.
Salmonella enterica
C.
Clostridium botulinum
D.
Listeria monocytogenes
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Solution
Vibrio cholerae is the bacterium that causes cholera, leading to severe diarrhea and dehydration.
Correct Answer: A — Vibrio cholerae
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Q. Which pathogen is known to cause the disease known as 'flesh-eating disease'?
A.
Clostridium perfringens
B.
Streptococcus pyogenes
C.
Vibrio cholerae
D.
Listeria monocytogenes
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Solution
Streptococcus pyogenes is associated with necrotizing fasciitis, commonly referred to as 'flesh-eating disease'.
Correct Answer: B — Streptococcus pyogenes
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Q. Which type of hypersensitivity reaction is associated with allergic responses?
A.
Type I
B.
Type II
C.
Type III
D.
Type IV
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Solution
Type I hypersensitivity reactions are immediate allergic responses mediated by IgE antibodies.
Correct Answer: A — Type I
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Q. Which type of immune response is characterized by the production of antibodies?
A.
Cell-mediated immunity
B.
Humoral immunity
C.
Innate immunity
D.
Adaptive immunity
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Solution
Humoral immunity is characterized by the production of antibodies by B cells in response to antigens.
Correct Answer: B — Humoral immunity
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Q. Which type of immune response is characterized by the rapid production of antibodies upon re-exposure to an antigen?
A.
Primary response
B.
Secondary response
C.
Tertiary response
D.
Innate response
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Solution
The secondary immune response is characterized by a rapid and robust production of antibodies upon re-exposure to an antigen.
Correct Answer: B — Secondary response
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Q. Which type of immunity is conferred by the transfer of maternal antibodies to the fetus?
A.
Active immunity
B.
Passive immunity
C.
Innate immunity
D.
Cell-mediated immunity
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Solution
Passive immunity is conferred by the transfer of maternal antibodies to the fetus, providing temporary protection against infections.
Correct Answer: B — Passive immunity
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Q. Which type of immunity is primarily mediated by antibodies?
A.
Cell-mediated immunity
B.
Humoral immunity
C.
Innate immunity
D.
Passive immunity
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Solution
Humoral immunity is primarily mediated by antibodies produced by B cells, which help neutralize pathogens and mark them for destruction.
Correct Answer: B — Humoral immunity
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Q. Which type of immunity is provided by vaccination?
A.
Innate immunity
B.
Passive immunity
C.
Active immunity
D.
Cell-mediated immunity
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Solution
Vaccination stimulates the immune system to produce an active immune response, leading to the development of active immunity.
Correct Answer: C — Active immunity
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Q. Which type of pathogen is most commonly associated with foodborne illnesses?
A.
Bacteria
B.
Viruses
C.
Fungi
D.
Parasites
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Solution
Bacteria are the most common pathogens associated with foodborne illnesses, such as Salmonella and E. coli.
Correct Answer: A — Bacteria
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Q. Which type of T cell is primarily responsible for the direct killing of infected host cells?
A.
Helper T cells
B.
Cytotoxic T cells
C.
Regulatory T cells
D.
Memory T cells
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Solution
Cytotoxic T cells (CD8+ T cells) are responsible for directly killing infected cells by recognizing antigens presented by MHC class I molecules.
Correct Answer: B — Cytotoxic T cells
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Q. Which type of vaccine contains live attenuated pathogens?
A.
Inactivated vaccine
B.
Subunit vaccine
C.
Recombinant vaccine
D.
Live attenuated vaccine
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Solution
Live attenuated vaccines contain weakened forms of the pathogen that can still elicit an immune response without causing disease.
Correct Answer: D — Live attenuated vaccine
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Q. Which type of vaccine is composed of live attenuated pathogens?
A.
Inactivated vaccine
B.
Subunit vaccine
C.
Recombinant vaccine
D.
Live attenuated vaccine
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Solution
Live attenuated vaccines contain live pathogens that have been weakened so they cannot cause disease but still elicit a strong immune response.
Correct Answer: D — Live attenuated vaccine
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Q. Which vaccine is used to prevent measles?
A.
DTP vaccine
B.
MMR vaccine
C.
Hepatitis B vaccine
D.
Influenza vaccine
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Solution
The MMR vaccine protects against measles, mumps, and rubella, and is typically administered in childhood.
Correct Answer: B — MMR vaccine
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Q. Which vaccine type contains live attenuated pathogens?
A.
Inactivated vaccines
B.
Subunit vaccines
C.
Live attenuated vaccines
D.
Toxoid vaccines
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Solution
Live attenuated vaccines contain weakened forms of the pathogen that can still elicit an immune response.
Correct Answer: C — Live attenuated vaccines
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Q. Which vaccine type is most effective in inducing a strong cell-mediated immune response?
A.
Inactivated vaccines
B.
Live attenuated vaccines
C.
Subunit vaccines
D.
Toxoid vaccines
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Solution
Live attenuated vaccines are effective in inducing strong cell-mediated immune responses due to their ability to replicate and mimic natural infection.
Correct Answer: B — Live attenuated vaccines
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