Reaction Mechanisms: Substitution, Addition, Elimination - Case Studies

Q. In the reaction of benzyl chloride with sodium hydroxide, which mechanism is primarily involved?
  • A. SN1
  • B. SN2
  • C. E1
  • D. E2
Q. What is the expected major product when 1-chloropropane reacts with potassium tert-butoxide?
  • A. Propene
  • B. 2-propanol
  • C. 1-butene
  • D. 2-bromopropane
Q. What is the IUPAC name for the compound with the formula C4H9Br?
  • A. 1-bromobutane
  • B. 2-bromobutane
  • C. 1-bromopropane
  • D. 2-bromopropane
Q. What is the IUPAC name of the compound with the structure CH3-CH2-CH(CH3)-Br?
  • A. 1-bromo-2-methylpropane
  • B. 2-bromo-3-methylbutane
  • C. 3-bromobutane
  • D. 1-bromo-3-methylbutane
Q. What is the main mechanism for the reaction of 1-bromopropane with sodium hydroxide in ethanol?
  • A. SN1
  • B. SN2
  • C. E1
  • D. E2
Q. What is the main mechanism of the reaction between 1-bromopropane and sodium hydroxide in ethanol?
  • A. SN1
  • B. SN2
  • C. E1
  • D. E2
Q. What is the product of the E2 elimination of 2-bromobutane?
  • A. Butene
  • B. 2-butene
  • C. 1-butene
  • D. Butyne
Q. What is the stereochemical outcome of an SN2 reaction?
  • A. Retention of configuration
  • B. Inversion of configuration
  • C. Racemization
  • D. No stereochemical change
Q. What type of stereochemistry is observed in the product of an E2 elimination reaction?
  • A. R/S configuration
  • B. Cis/Trans isomerism
  • C. Z/E isomerism
  • D. Anti-periplanar arrangement
Q. Which of the following is a strong nucleophile that can participate in an SN2 reaction?
  • A. Water
  • B. Ethanol
  • C. Sodium hydroxide
  • D. Acetic acid
Q. Which of the following statements is true regarding nucleophilic substitution reactions?
  • A. SN1 reactions are favored by tertiary substrates
  • B. SN2 reactions are favored by tertiary substrates
  • C. SN1 reactions require a strong nucleophile
  • D. SN2 reactions occur in two steps
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