Reaction Mechanisms: Substitution, Addition, Elimination - Case Studies
Q. In the reaction of benzyl chloride with sodium hydroxide, which mechanism is primarily involved?
A.SN1
B.SN2
C.E1
D.E2
Solution
The reaction of benzyl chloride with sodium hydroxide primarily follows the SN1 mechanism due to the stability of the benzyl carbocation formed during the reaction.
Q. What is the main mechanism for the reaction of 1-bromopropane with sodium hydroxide in ethanol?
A.SN1
B.SN2
C.E1
D.E2
Solution
The reaction of 1-bromopropane with sodium hydroxide in ethanol proceeds via the SN2 mechanism due to the primary nature of the substrate, allowing for a backside attack.
Q. What is the main mechanism of the reaction between 1-bromopropane and sodium hydroxide in ethanol?
A.SN1
B.SN2
C.E1
D.E2
Solution
The reaction between 1-bromopropane and sodium hydroxide in ethanol proceeds via the SN2 mechanism due to the primary nature of the alkyl halide, allowing for a direct nucleophilic attack.
Q. What is the product of the E2 elimination of 2-bromobutane?
A.Butene
B.2-butene
C.1-butene
D.Butyne
Solution
The E2 elimination of 2-bromobutane primarily yields 2-butene as the product due to the formation of a double bond between the second and third carbons.
Q. Which of the following statements is true regarding nucleophilic substitution reactions?
A.SN1 reactions are favored by tertiary substrates
B.SN2 reactions are favored by tertiary substrates
C.SN1 reactions require a strong nucleophile
D.SN2 reactions occur in two steps
Solution
SN1 reactions are favored by tertiary substrates due to the stability of the carbocation formed, while SN2 reactions are favored by primary substrates.
Correct Answer: A — SN1 reactions are favored by tertiary substrates