Which cytokine is primarily responsible for the differentiation of naive T cells into Th1 cells?
Practice Questions
1 question
Q1
Which cytokine is primarily responsible for the differentiation of naive T cells into Th1 cells?
IL-4
IL-12
IFN-gamma
TNF-alpha
IL-12 is the key cytokine that promotes the differentiation of naive T cells into Th1 cells, which are important for cell-mediated immunity.
Questions & Step-by-step Solutions
1 item
Q
Q: Which cytokine is primarily responsible for the differentiation of naive T cells into Th1 cells?
Solution: IL-12 is the key cytokine that promotes the differentiation of naive T cells into Th1 cells, which are important for cell-mediated immunity.
Steps: 6
Step 1: Understand what naive T cells are. They are a type of immune cell that has not yet been activated by an infection.
Step 2: Learn about cytokines. Cytokines are signaling proteins that help regulate immune responses.
Step 3: Identify the role of Th1 cells. Th1 cells are a subtype of T cells that help fight off certain infections, especially those caused by viruses and some bacteria.
Step 4: Find out which cytokine is important for the development of Th1 cells. The key cytokine is IL-12.
Step 5: Know that IL-12 is produced by certain immune cells when there is an infection, signaling naive T cells to become Th1 cells.
Step 6: Conclude that IL-12 is essential for the differentiation of naive T cells into Th1 cells.
