In eukaryotic cells, what modification occurs to pre-mRNA before it becomes mature mRNA?
Practice Questions
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Q1
In eukaryotic cells, what modification occurs to pre-mRNA before it becomes mature mRNA?
Addition of a poly-A tail and 5' cap
Splicing out of exons
Replication of DNA
Translation into protein
Pre-mRNA undergoes capping at the 5' end and polyadenylation at the 3' end, along with splicing to remove introns, to become mature mRNA.
Questions & Step-by-step Solutions
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Q
Q: In eukaryotic cells, what modification occurs to pre-mRNA before it becomes mature mRNA?
Solution: Pre-mRNA undergoes capping at the 5' end and polyadenylation at the 3' end, along with splicing to remove introns, to become mature mRNA.
Steps: 5
Step 1: Start with pre-mRNA, which is the initial form of mRNA that is not yet ready for translation.
Step 2: Add a special cap (5' cap) to the beginning (5' end) of the pre-mRNA. This helps protect the mRNA and assists in the process of translation.
Step 3: Add a long tail of adenine nucleotides (poly-A tail) to the end (3' end) of the pre-mRNA. This also helps protect the mRNA and aids in its stability.
Step 4: Remove non-coding regions called introns from the pre-mRNA. This process is called splicing. The remaining coding regions, called exons, are joined together.
Step 5: After these modifications, the pre-mRNA is now mature mRNA and is ready to be translated into a protein.