What is the stereochemical configuration of the product formed from the reaction

Practice Questions

Q1
What is the stereochemical configuration of the product formed from the reaction of (R)-2-bromobutane with a strong nucleophile in an S_N2 reaction?
  1. R
  2. S
  3. R and S
  4. No stereochemical change

Questions & Step-by-Step Solutions

What is the stereochemical configuration of the product formed from the reaction of (R)-2-bromobutane with a strong nucleophile in an S_N2 reaction?
  • Step 1: Identify the starting material, which is (R)-2-bromobutane. This means the molecule has a specific 3D arrangement of atoms.
  • Step 2: Understand that an S_N2 reaction involves a strong nucleophile attacking the carbon atom that is bonded to the bromine atom (the leaving group).
  • Step 3: Recognize that in an S_N2 reaction, the nucleophile attacks from the opposite side of the leaving group (bromine), leading to a change in the configuration.
  • Step 4: Since the starting material is (R)-2-bromobutane, the attack by the nucleophile will cause the configuration to invert.
  • Step 5: Conclude that the product will have the (S) configuration due to this inversion.
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