Which of the following methods can be used to prepare primary amines?
Practice Questions
Q1
Which of the following methods can be used to prepare primary amines?
Reduction of nitriles
Hydrolysis of amides
Alkylation of ammonia
All of the above
Questions & Step-by-Step Solutions
Which of the following methods can be used to prepare primary amines?
Step 1: Understand what primary amines are. Primary amines are organic compounds that contain one amino group (-NH2) attached to a carbon atom.
Step 2: Learn about nitriles. Nitriles are compounds that contain a cyano group (-C≡N). They can be reduced to form primary amines.
Step 3: Know the reduction process. The reduction of nitriles typically involves using hydrogen gas and a catalyst or other reducing agents to convert the nitrile to a primary amine.
Step 4: Understand amides. Amides are compounds that contain a carbonyl group (C=O) attached to a nitrogen atom. Hydrolysis of amides can also produce primary amines.
Step 5: Learn about hydrolysis. Hydrolysis of amides involves adding water and sometimes an acid or base to break the amide bond, resulting in a primary amine.
Step 6: Explore alkylation of ammonia. This method involves reacting ammonia (NH3) with an alkyl halide (R-X) to form a primary amine.
Step 7: Remember that the alkyl halide should be a primary halide to ensure the formation of a primary amine.
