Which of the following mutations is likely to have the most significant impact o
Practice Questions
Q1
Which of the following mutations is likely to have the most significant impact on protein function?
Silent mutation
Missense mutation
Nonsense mutation
Frameshift mutation
Questions & Step-by-Step Solutions
Which of the following mutations is likely to have the most significant impact on protein function?
Correct Answer: Frameshift mutation
Step 1: Understand what a mutation is. A mutation is a change in the DNA sequence.
Step 2: Learn about different types of mutations. Common types include point mutations, insertions, deletions, and frameshift mutations.
Step 3: Know what a frameshift mutation is. It occurs when nucleotides are added or removed from the DNA sequence, changing how the sequence is read.
Step 4: Realize that the genetic code is read in groups of three nucleotides called codons, which correspond to specific amino acids.
Step 5: Understand that a frameshift mutation changes the reading frame, which can lead to a completely different sequence of amino acids.
Step 6: Recognize that this can result in a nonfunctional protein because the structure and function of proteins depend on their amino acid sequence.
Step 7: Compare frameshift mutations to other mutations. Point mutations may change one amino acid, but frameshift mutations can change many amino acids.
Step 8: Conclude that frameshift mutations are likely to have the most significant impact on protein function.
