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What is a frameshift mutation?

Practice Questions

Q1
What is a frameshift mutation?
  1. A mutation that changes one amino acid
  2. A mutation that adds or removes nucleotides, altering the reading frame
  3. A mutation that occurs in non-coding regions
  4. A mutation that duplicates a segment of DNA

Questions & Step-by-Step Solutions

What is a frameshift mutation?
  • Step 1: Understand that DNA is made up of building blocks called nucleotides.
  • Step 2: Know that these nucleotides are read in groups of three, called codons, to make proteins.
  • Step 3: A frameshift mutation happens when one or more nucleotides are added or removed from the DNA sequence.
  • Step 4: This addition or deletion changes how the remaining nucleotides are grouped into codons.
  • Step 5: Because the grouping changes, the sequence of amino acids that are made can also change.
  • Step 6: This can lead to a completely different protein, which may not function properly.
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