Which of the following mutations is likely to have the most significant effect o
Practice Questions
Q1
Which of the following mutations is likely to have the most significant effect on a protein?
Silent mutation
Missense mutation
Nonsense mutation
In-frame mutation
Questions & Step-by-Step Solutions
Which of the following mutations is likely to have the most significant effect on a protein?
Step 1: Understand what a mutation is. A mutation is a change in the DNA sequence.
Step 2: Learn about different types of mutations. Common types include point mutations, insertions, deletions, and nonsense mutations.
Step 3: Focus on nonsense mutations. A nonsense mutation changes a codon (a sequence of three DNA bases) into a stop codon.
Step 4: Recognize what a stop codon does. A stop codon signals the end of protein synthesis.
Step 5: Realize the impact of a nonsense mutation. It can cause the protein to be shorter than normal, which often makes it nonfunctional.
Step 6: Compare this to other mutations. While other mutations can also affect proteins, a nonsense mutation usually has a more drastic effect because it stops the protein from being made completely.
