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In eukaryotic cells, what modification occurs to pre-mRNA before it becomes matu

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Question: In eukaryotic cells, what modification occurs to pre-mRNA before it becomes mature mRNA?

Options:

  1. Addition of a poly-A tail and 5\' cap
  2. Splicing out of exons
  3. Replication of DNA
  4. Translation into protein

Correct Answer: Addition of a poly-A tail and 5\' cap

Solution:

Pre-mRNA undergoes capping at the 5\' end and polyadenylation at the 3\' end, along with splicing to remove introns, to become mature mRNA.

In eukaryotic cells, what modification occurs to pre-mRNA before it becomes matu

Practice Questions

Q1
In eukaryotic cells, what modification occurs to pre-mRNA before it becomes mature mRNA?
  1. Addition of a poly-A tail and 5' cap
  2. Splicing out of exons
  3. Replication of DNA
  4. Translation into protein

Questions & Step-by-Step Solutions

In eukaryotic cells, what modification occurs to pre-mRNA before it becomes mature mRNA?
Correct Answer: Pre-mRNA undergoes capping, polyadenylation, and splicing.
  • Step 1: Start with pre-mRNA, which is the initial form of mRNA that is not yet ready for translation.
  • Step 2: Add a special cap (5' cap) to the beginning (5' end) of the pre-mRNA. This helps protect the mRNA and assists in the process of translation.
  • Step 3: Add a long tail of adenine nucleotides (poly-A tail) to the end (3' end) of the pre-mRNA. This also helps protect the mRNA and aids in its stability.
  • Step 4: Remove non-coding regions called introns from the pre-mRNA. This process is called splicing. The remaining coding regions, called exons, are joined together.
  • Step 5: After these modifications, the pre-mRNA is now mature mRNA and is ready to be translated into a protein.
  • Pre-mRNA Processing – The modifications that pre-mRNA undergoes to become mature mRNA, including capping, polyadenylation, and splicing.
  • Capping – The addition of a modified guanine nucleotide to the 5' end of the pre-mRNA.
  • Polyadenylation – The addition of a poly(A) tail to the 3' end of the pre-mRNA.
  • Splicing – The removal of non-coding sequences (introns) from the pre-mRNA.
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