What is the mechanism of action of SSRIs (Selective Serotonin Reuptake Inhibitor

Practice Questions

Q1
What is the mechanism of action of SSRIs (Selective Serotonin Reuptake Inhibitors)?
  1. Inhibition of serotonin reuptake
  2. Inhibition of dopamine receptors
  3. Inhibition of norepinephrine reuptake
  4. Activation of serotonin receptors

Questions & Step-by-Step Solutions

What is the mechanism of action of SSRIs (Selective Serotonin Reuptake Inhibitors)?
  • Step 1: Understand that serotonin is a chemical in the brain that helps regulate mood.
  • Step 2: Know that neurons (brain cells) communicate with each other using chemicals like serotonin.
  • Step 3: When a neuron sends serotonin to another neuron, some of it is taken back (reuptake) into the first neuron.
  • Step 4: SSRIs are medications that block this reuptake process.
  • Step 5: By blocking reuptake, SSRIs allow more serotonin to stay in the space between neurons (called the synaptic cleft).
  • Step 6: More serotonin in the synaptic cleft means that the receiving neuron can use more serotonin, which can help improve mood.
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