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What is the primary barrier to drug absorption in the gastrointestinal tract?

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Question: What is the primary barrier to drug absorption in the gastrointestinal tract?

Options:

  1. Mucosal layer
  2. Epithelial cells
  3. Blood-brain barrier
  4. Liver metabolism

Correct Answer: Epithelial cells

Solution: 

The primary barrier to drug absorption in the gastrointestinal tract is the epithelial cells that line the gut, which must be crossed for absorption to occur.

What is the primary barrier to drug absorption in the gastrointestinal tract?

Practice Questions

Q1
What is the primary barrier to drug absorption in the gastrointestinal tract?
  1. Mucosal layer
  2. Epithelial cells
  3. Blood-brain barrier
  4. Liver metabolism

Questions & Step-by-Step Solutions

What is the primary barrier to drug absorption in the gastrointestinal tract?
  • Step 1: Understand that the gastrointestinal tract is the pathway food and drugs travel through in the body.
  • Step 2: Recognize that the inside of the gastrointestinal tract is lined with a layer of cells called epithelial cells.
  • Step 3: Know that these epithelial cells act as a barrier that drugs must pass through to enter the bloodstream.
  • Step 4: Conclude that the primary barrier to drug absorption is these epithelial cells, as they control what gets absorbed.
No concepts available.
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