Which of the following can significantly affect the volume of distribution of a
Practice Questions
Q1
Which of the following can significantly affect the volume of distribution of a drug?
Body fat percentage
Age of the patient
Gender of the patient
All of the above
Questions & Step-by-Step Solutions
Which of the following can significantly affect the volume of distribution of a drug?
Step 1: Understand what volume of distribution (Vd) means. It is a measure of how much a drug spreads throughout the body compared to the amount of drug in the blood.
Step 2: Identify factors that can affect Vd. These can include body weight, age, gender, and health conditions.
Step 3: Recognize that body composition (like fat and water content) can change how a drug is distributed in the body.
Step 4: Realize that drug binding to proteins in the blood can also influence how much of the drug is available to act in the body.
Step 5: Conclude that all these factors together can significantly affect the volume of distribution of a drug.
