What is the effect of alcohol on the metabolism of acetaminophen?

Practice Questions

Q1
What is the effect of alcohol on the metabolism of acetaminophen?
  1. Increases its metabolism to non-toxic metabolites
  2. Decreases its metabolism, increasing toxicity
  3. Increases its metabolism to toxic metabolites
  4. Has no effect on its metabolism

Questions & Step-by-Step Solutions

What is the effect of alcohol on the metabolism of acetaminophen?
  • Step 1: Understand what acetaminophen is. It is a common pain reliever and fever reducer.
  • Step 2: Learn about alcohol. It is a substance that can affect how the body processes other drugs.
  • Step 3: Know that the liver is responsible for breaking down both alcohol and acetaminophen.
  • Step 4: Recognize that chronic alcohol consumption means drinking alcohol regularly over a long period.
  • Step 5: Understand that chronic alcohol consumption can increase the production of an enzyme called CYP2E1 in the liver.
  • Step 6: Realize that CYP2E1 helps break down acetaminophen into different substances, some of which can be harmful.
  • Step 7: Learn that when acetaminophen is broken down into these harmful substances, it can lead to liver damage.
  • Step 8: Conclude that drinking alcohol regularly can make acetaminophen more dangerous to the liver.
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