What is the primary concern when combining MAO inhibitors with tyramine-rich foo

Practice Questions

Q1
What is the primary concern when combining MAO inhibitors with tyramine-rich foods?
  1. Hypoglycemia
  2. Hypertensive crisis
  3. Serotonin syndrome
  4. Cardiac arrhythmias

Questions & Step-by-Step Solutions

What is the primary concern when combining MAO inhibitors with tyramine-rich foods?
  • Step 1: Understand what MAO inhibitors are. They are medications that help treat depression by blocking the enzyme monoamine oxidase.
  • Step 2: Learn about tyramine. Tyramine is a substance found in certain foods, like aged cheese and cured meats.
  • Step 3: Know that MAO inhibitors prevent the breakdown of tyramine in the body.
  • Step 4: Realize that when tyramine levels rise too high, it can cause the body to release too much norepinephrine, a chemical that raises blood pressure.
  • Step 5: Understand that this excessive norepinephrine can lead to a hypertensive crisis, which is a dangerous increase in blood pressure.
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