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What is the effect of St. John's Wort on the metabolism of certain drugs?

Practice Questions

Q1
What is the effect of St. John's Wort on the metabolism of certain drugs?
  1. Inhibits CYP450 enzymes
  2. Induces CYP450 enzymes
  3. Has no effect on drug metabolism
  4. Inhibits P-glycoprotein

Questions & Step-by-Step Solutions

What is the effect of St. John's Wort on the metabolism of certain drugs?
  • Step 1: Understand what St. John's Wort is. It is a herbal supplement often used for depression.
  • Step 2: Learn about CYP450 enzymes. These are enzymes in the liver that help break down many drugs.
  • Step 3: Know that St. John's Wort can increase the activity of these CYP450 enzymes.
  • Step 4: Realize that when CYP450 enzymes are induced, they can break down certain drugs faster.
  • Step 5: Understand that if drugs are broken down too quickly, they may not work as well, leading to decreased effectiveness.
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