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What is the primary mechanism of action for warfarin?

Practice Questions

Q1
What is the primary mechanism of action for warfarin?
  1. Inhibition of vitamin K epoxide reductase
  2. Inhibition of thromboxane A2 synthesis
  3. Activation of antithrombin III
  4. Inhibition of platelet aggregation

Questions & Step-by-Step Solutions

What is the primary mechanism of action for warfarin?
  • Step 1: Understand that warfarin is a medication used to prevent blood clots.
  • Step 2: Learn that blood clotting requires certain proteins called clotting factors.
  • Step 3: Know that some of these clotting factors depend on vitamin K to be made in the body.
  • Step 4: Identify that warfarin works by blocking a specific enzyme called vitamin K epoxide reductase.
  • Step 5: Realize that by inhibiting this enzyme, warfarin reduces the amount of active vitamin K available.
  • Step 6: Conclude that with less active vitamin K, the body cannot produce enough clotting factors, which helps prevent blood clots.
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