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What is the role of integrase in the life cycle of Retroviridae?

Practice Questions

Q1
What is the role of integrase in the life cycle of Retroviridae?
  1. To replicate RNA
  2. To integrate viral DNA into the host genome
  3. To package viral proteins
  4. To synthesize viral proteins

Questions & Step-by-Step Solutions

What is the role of integrase in the life cycle of Retroviridae?
  • Step 1: A retrovirus enters a host cell and releases its RNA into the cell.
  • Step 2: The viral RNA is converted into DNA by an enzyme called reverse transcriptase.
  • Step 3: The newly formed viral DNA is then transported into the nucleus of the host cell.
  • Step 4: Integrase, an enzyme produced by the retrovirus, attaches to the viral DNA.
  • Step 5: Integrase helps the viral DNA to insert itself into the host cell's DNA (genome).
  • Step 6: Once integrated, the viral DNA can be used by the host cell to produce new viral particles.
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