During DNA replication, which direction does the DNA polymerase synthesize the n

Practice Questions

Q1
During DNA replication, which direction does the DNA polymerase synthesize the new strand?
  1. 5' to 3'
  2. 3' to 5'
  3. Both directions
  4. Randomly

Questions & Step-by-Step Solutions

During DNA replication, which direction does the DNA polymerase synthesize the new strand?
  • Step 1: Understand that DNA is made up of two strands that run in opposite directions.
  • Step 2: Know that each strand has a direction indicated by numbers: 5' (five prime) and 3' (three prime).
  • Step 3: Remember that DNA polymerase is the enzyme that builds new DNA strands.
  • Step 4: Learn that DNA polymerase can only add new nucleotides to the 3' end of a growing DNA strand.
  • Step 5: Conclude that because it adds nucleotides to the 3' end, the new strand is synthesized in the 5' to 3' direction.
  • Direction of DNA Synthesis – DNA polymerase can only add nucleotides to the 3' end of a growing DNA strand, thus synthesizing in the 5' to 3' direction.
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