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What is the primary target of sulfonamides?

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Question: What is the primary target of sulfonamides?

Options:

  1. DNA gyrase
  2. Dihydropteroate synthase
  3. RNA polymerase
  4. Peptidoglycan

Correct Answer: Dihydropteroate synthase

Solution: 

Sulfonamides target dihydropteroate synthase, inhibiting folic acid synthesis.

What is the primary target of sulfonamides?

Practice Questions

Q1
What is the primary target of sulfonamides?
  1. DNA gyrase
  2. Dihydropteroate synthase
  3. RNA polymerase
  4. Peptidoglycan

Questions & Step-by-Step Solutions

What is the primary target of sulfonamides?
  • Step 1: Understand that sulfonamides are a type of antibiotic.
  • Step 2: Learn that antibiotics work by targeting specific processes in bacteria.
  • Step 3: Identify that sulfonamides specifically target an enzyme called dihydropteroate synthase.
  • Step 4: Know that this enzyme is important for bacteria to make folic acid.
  • Step 5: Realize that by inhibiting dihydropteroate synthase, sulfonamides stop bacteria from producing folic acid.
  • Step 6: Conclude that without folic acid, bacteria cannot grow and multiply.
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