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What is the primary target of sulfonamides?

Practice Questions

Q1
What is the primary target of sulfonamides?
  1. DNA gyrase
  2. Dihydropteroate synthase
  3. RNA polymerase
  4. Peptidoglycan

Questions & Step-by-Step Solutions

What is the primary target of sulfonamides?
  • Step 1: Understand that sulfonamides are a type of antibiotic.
  • Step 2: Learn that antibiotics work by targeting specific processes in bacteria.
  • Step 3: Identify that sulfonamides specifically target an enzyme called dihydropteroate synthase.
  • Step 4: Know that this enzyme is important for bacteria to make folic acid.
  • Step 5: Realize that by inhibiting dihydropteroate synthase, sulfonamides stop bacteria from producing folic acid.
  • Step 6: Conclude that without folic acid, bacteria cannot grow and multiply.
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