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What is the mechanism of action of tetracyclines?

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Question: What is the mechanism of action of tetracyclines?

Options:

  1. Inhibition of cell wall synthesis
  2. Inhibition of protein synthesis
  3. Inhibition of nucleic acid synthesis
  4. Inhibition of folic acid synthesis

Correct Answer: Inhibition of protein synthesis

Solution: 

Tetracyclines inhibit protein synthesis by binding to the 30S ribosomal subunit.

What is the mechanism of action of tetracyclines?

Practice Questions

Q1
What is the mechanism of action of tetracyclines?
  1. Inhibition of cell wall synthesis
  2. Inhibition of protein synthesis
  3. Inhibition of nucleic acid synthesis
  4. Inhibition of folic acid synthesis

Questions & Step-by-Step Solutions

What is the mechanism of action of tetracyclines?
  • Step 1: Understand that tetracyclines are a type of antibiotic.
  • Step 2: Know that antibiotics work by stopping bacteria from growing or killing them.
  • Step 3: Learn that proteins are essential for bacteria to function and grow.
  • Step 4: Recognize that proteins are made by ribosomes in the bacteria.
  • Step 5: Identify that ribosomes have two parts: the 30S subunit and the 50S subunit.
  • Step 6: Understand that tetracyclines specifically target and bind to the 30S ribosomal subunit.
  • Step 7: Realize that by binding to the 30S subunit, tetracyclines prevent the bacteria from making proteins.
  • Step 8: Conclude that without proteins, bacteria cannot grow or multiply, which helps to eliminate the infection.
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