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Which step of the TCA cycle produces FADH2?

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Question: Which step of the TCA cycle produces FADH2?

Options:

  1. Conversion of succinate to fumarate
  2. Conversion of isocitrate to alpha-ketoglutarate
  3. Conversion of malate to oxaloacetate
  4. Conversion of citrate to isocitrate

Correct Answer: Conversion of succinate to fumarate

Solution: 

The conversion of succinate to fumarate produces FADH2 in the TCA cycle.

Which step of the TCA cycle produces FADH2?

Practice Questions

Q1
Which step of the TCA cycle produces FADH2?
  1. Conversion of succinate to fumarate
  2. Conversion of isocitrate to alpha-ketoglutarate
  3. Conversion of malate to oxaloacetate
  4. Conversion of citrate to isocitrate

Questions & Step-by-Step Solutions

Which step of the TCA cycle produces FADH2?
  • Step 1: The TCA cycle starts with a molecule called acetyl-CoA combining with oxaloacetate to form citrate.
  • Step 2: Citrate is then converted into isocitrate.
  • Step 3: Isocitrate is converted into alpha-ketoglutarate, producing NADH.
  • Step 4: Alpha-ketoglutarate is converted into succinyl-CoA, producing another NADH.
  • Step 5: Succinyl-CoA is converted into succinate, producing GTP or ATP.
  • Step 6: Succinate is converted into fumarate, and this step produces FADH2.
  • Step 7: Fumarate is converted into malate.
  • Step 8: Malate is converted back into oxaloacetate, producing another NADH.
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