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What is the effect of pH on peptide solubility?
Practice Questions
Q1
What is the effect of pH on peptide solubility?
It has no effect
It can increase solubility at all pH levels
It can decrease solubility at certain pH levels
It only affects hydrophobic peptides
Questions & Step-by-Step Solutions
What is the effect of pH on peptide solubility?
Steps
Concepts
Step 1: Understand that peptides are made of amino acids, which have different parts that can be charged (ionized) depending on the pH.
Step 2: Know that pH is a measure of how acidic or basic a solution is, which can affect the charge of the amino acids in the peptide.
Step 3: Realize that when the pH changes, it can cause some amino acids to gain or lose protons (H+ ions), changing their charge.
Step 4: Remember that charged amino acids tend to be more soluble in water, while neutral ones may be less soluble.
Step 5: Conclude that at different pH levels, the solubility of the peptide can increase or decrease based on the overall charge of the peptide.
No concepts available.
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