Which of the following is a common method for studying protein-nucleic acid inte

Which of the following is a common method for studying protein-nucleic acid interactions?

Which of the following is a common method for studying protein-nucleic acid interactions?

Step 1: Understand that proteins can interact with nucleic acids (like DNA or RNA).
Step 2: Learn about a method called Electrophoretic Mobility Shift Assay (EMSA).
Step 3: Know that EMSA involves mixing proteins with nucleic acids.
Step 4: Prepare a gel for electrophoresis, which is a technique to separate molecules based on their size and charge.
Step 5: Load the mixture of proteins and nucleic acids onto the gel.
Step 6: Apply an electric current to the gel, causing the molecules to move.
Step 7: Observe how the mobility of the nucleic acids changes when they bind to proteins.
Step 8: Analyze the results to see if there are shifts in the position of the nucleic acids on the gel, indicating an interaction with proteins.

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