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What is the role of DNA ligase in DNA replication?

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Question: What is the role of DNA ligase in DNA replication?

Options:

  1. Unwinds DNA
  2. Synthesizes RNA primers
  3. Joins Okazaki fragments
  4. Adds nucleotides

Correct Answer: Joins Okazaki fragments

Solution: 

DNA ligase joins Okazaki fragments on the lagging strand during DNA replication.

What is the role of DNA ligase in DNA replication?

Practice Questions

Q1
What is the role of DNA ligase in DNA replication?
  1. Unwinds DNA
  2. Synthesizes RNA primers
  3. Joins Okazaki fragments
  4. Adds nucleotides

Questions & Step-by-Step Solutions

What is the role of DNA ligase in DNA replication?
  • Step 1: Understand that DNA replication is the process of copying DNA.
  • Step 2: Know that DNA has two strands that separate during replication.
  • Step 3: Realize that one strand (the leading strand) is copied continuously.
  • Step 4: Understand that the other strand (the lagging strand) is copied in small pieces called Okazaki fragments.
  • Step 5: Learn that DNA ligase is an enzyme that helps join these Okazaki fragments together.
  • Step 6: Conclude that DNA ligase is essential for making the lagging strand a continuous piece of DNA.
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