Which of the following is an example of an allosteric inhibitor?

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Question: Which of the following is an example of an allosteric inhibitor?

Options:

Correct Answer: Citrate

Solution:

Citrate acts as an allosteric inhibitor of phosphofructokinase, regulating glycolysis.

Which of the following is an example of an allosteric inhibitor?

Which of the following is an example of an allosteric inhibitor?

Step 1: Understand what an allosteric inhibitor is. An allosteric inhibitor is a molecule that binds to an enzyme at a site other than the active site, changing the enzyme's shape and reducing its activity.
Step 2: Identify the enzyme in the question. The enzyme mentioned is phosphofructokinase, which is important in the process of glycolysis (the breakdown of glucose for energy).
Step 3: Look for examples of molecules that can act as allosteric inhibitors. Citrate is one such molecule that can bind to phosphofructokinase.
Step 4: Confirm that citrate reduces the activity of phosphofructokinase when it binds, thus acting as an allosteric inhibitor.
Step 5: Conclude that citrate is indeed an example of an allosteric inhibitor.

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