What is the product of the reaction between an amine and an acyl chloride?
Practice Questions
1 question
Q1
What is the product of the reaction between an amine and an acyl chloride?
Amide
Ester
Carboxylic acid
Alcohol
Amines react with acyl chlorides to form amides through a nucleophilic acyl substitution reaction.
Questions & Step-by-step Solutions
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Q
Q: What is the product of the reaction between an amine and an acyl chloride?
Solution: Amines react with acyl chlorides to form amides through a nucleophilic acyl substitution reaction.
Steps: 5
Step 1: Identify the reactants - you have an amine (which contains a nitrogen atom) and an acyl chloride (which contains a carbonyl group, C=O, and a chlorine atom).
Step 2: Understand that the nitrogen in the amine is nucleophilic, meaning it can donate a pair of electrons.
Step 3: The amine attacks the carbon atom of the acyl chloride, which is bonded to the chlorine atom. This is called nucleophilic acyl substitution.
Step 4: When the amine attacks, the chlorine atom leaves, resulting in the formation of a new bond between the nitrogen of the amine and the carbon of the acyl chloride.
Step 5: The product formed is an amide, which has the structure R-C(=O)-NR'2, where R is the rest of the acyl chloride and NR'2 is the amine part.
