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If a test for a disease has a sensitivity of 90% and a specificity of 95%, what

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Question: If a test for a disease has a sensitivity of 90% and a specificity of 95%, what is the probability that a person who tests positive actually has the disease, given that the prevalence is 1%? (2022)

Options:

  1. 0.018
  2. 0.1
  3. 0.5
  4. 0.9

Correct Answer: 0.018

Exam Year: 2022

Solution:

Using Bayes\' theorem, P(Disease | Positive) = (Sensitivity Γ— Prevalence) / ((Sensitivity Γ— Prevalence) + (1 - Specificity) Γ— (1 - Prevalence)) = (0.9 Γ— 0.01) / ((0.9 Γ— 0.01) + (0.05 Γ— 0.99)) = 0.018.

If a test for a disease has a sensitivity of 90% and a specificity of 95%, what

Practice Questions

Q1
If a test for a disease has a sensitivity of 90% and a specificity of 95%, what is the probability that a person who tests positive actually has the disease, given that the prevalence is 1%? (2022)
  1. 0.018
  2. 0.1
  3. 0.5
  4. 0.9

Questions & Step-by-Step Solutions

If a test for a disease has a sensitivity of 90% and a specificity of 95%, what is the probability that a person who tests positive actually has the disease, given that the prevalence is 1%? (2022)
  • Step 1: Understand the terms. Sensitivity is the probability that the test correctly identifies a person with the disease. Specificity is the probability that the test correctly identifies a person without the disease. Prevalence is the actual proportion of people in the population who have the disease.
  • Step 2: Write down the values given in the question. Sensitivity = 90% = 0.9, Specificity = 95% = 0.95, Prevalence = 1% = 0.01.
  • Step 3: Calculate the probability of having the disease given a positive test result using Bayes' theorem. The formula is: P(Disease | Positive) = (Sensitivity Γ— Prevalence) / ((Sensitivity Γ— Prevalence) + (1 - Specificity) Γ— (1 - Prevalence)).
  • Step 4: Substitute the values into the formula. P(Disease | Positive) = (0.9 Γ— 0.01) / ((0.9 Γ— 0.01) + (0.05 Γ— 0.99)).
  • Step 5: Calculate the numerator: 0.9 Γ— 0.01 = 0.009.
  • Step 6: Calculate the denominator: (0.9 Γ— 0.01) + (0.05 Γ— 0.99) = 0.009 + 0.0495 = 0.0585.
  • Step 7: Divide the numerator by the denominator: 0.009 / 0.0585 = 0.1538.
  • Step 8: Convert the result to a percentage: 0.1538 Γ— 100 = 15.38%.
  • Step 9: The final answer is that the probability that a person who tests positive actually has the disease is approximately 15.38%.
  • Bayes' Theorem – A mathematical formula used to calculate the probability of a condition based on prior knowledge and new evidence.
  • Sensitivity and Specificity – Sensitivity measures the proportion of actual positives correctly identified, while specificity measures the proportion of actual negatives correctly identified.
  • Prevalence – The proportion of a population found to have a condition at a specific time.
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