What is the main mechanism for the reaction of 2-bromobutane with sodium hydroxi

Practice Questions

Q1
What is the main mechanism for the reaction of 2-bromobutane with sodium hydroxide in ethanol?
  1. SN1
  2. SN2
  3. E1
  4. E2

Questions & Step-by-Step Solutions

What is the main mechanism for the reaction of 2-bromobutane with sodium hydroxide in ethanol?
  • Step 1: Identify the reactants. We have 2-bromobutane and sodium hydroxide (NaOH) in ethanol.
  • Step 2: Recognize that 2-bromobutane is a secondary alkyl halide.
  • Step 3: Understand that sodium hydroxide provides hydroxide ions (OH-), which are strong nucleophiles.
  • Step 4: Recall that SN2 reactions involve a nucleophile attacking the carbon atom bonded to the leaving group (bromine in this case).
  • Step 5: Since 2-bromobutane is a secondary substrate, it can undergo an SN2 reaction, but it is less favorable than primary substrates.
  • Step 6: Conclude that the reaction will proceed via an SN2 mechanism because the strong nucleophile (OH-) can effectively attack the carbon and displace the bromine.
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