In an SN2 reaction, what is the stereochemical outcome when the nucleophile atta

Practice Questions

Q1
In an SN2 reaction, what is the stereochemical outcome when the nucleophile attacks a chiral center?
  1. Retention of configuration
  2. Inversion of configuration
  3. No change in configuration
  4. Formation of a racemic mixture

Questions & Step-by-Step Solutions

In an SN2 reaction, what is the stereochemical outcome when the nucleophile attacks a chiral center?
  • Step 1: Identify the chiral center in the molecule where the reaction will occur.
  • Step 2: Recognize that in an SN2 reaction, a nucleophile (a molecule that donates electrons) will attack the chiral center.
  • Step 3: Understand that the nucleophile approaches the chiral center from the side opposite to where the leaving group is located.
  • Step 4: Visualize that this attack causes the configuration of the chiral center to flip, which is called inversion.
  • Step 5: Conclude that the final product will have the opposite stereochemistry compared to the starting material.
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