Drug Absorption and Distribution MCQ & Objective Questions
Understanding "Drug Absorption and Distribution" is crucial for students preparing for various exams. This topic not only forms a fundamental part of pharmacology but also features prominently in MCQs and objective questions. By practicing these questions, students can enhance their exam preparation and improve their scores significantly.
What You Will Practise Here
Key concepts of drug absorption mechanisms
Factors affecting drug distribution in the body
Definitions of bioavailability and volume of distribution
Important formulas related to drug kinetics
Diagrams illustrating absorption pathways
Case studies on drug interactions and their effects
Commonly asked objective questions in exams
Exam Relevance
The topic of Drug Absorption and Distribution is frequently tested in CBSE, State Boards, NEET, and JEE exams. Students can expect questions that assess their understanding of drug kinetics, including definitions, calculations, and application-based scenarios. Common question patterns include multiple-choice questions that require students to identify factors influencing drug absorption or to calculate bioavailability based on given data.
Common Mistakes Students Make
Confusing the terms bioavailability and bioequivalence
Overlooking the impact of pH on drug solubility and absorption
Misunderstanding the role of plasma protein binding in drug distribution
Neglecting to consider the first-pass metabolism effect
Failing to apply theoretical knowledge to practical scenarios in questions
FAQs
Question: What is bioavailability? Answer: Bioavailability refers to the proportion of a drug that enters the circulation when introduced into the body and is available for therapeutic effect.
Question: How does the first-pass effect influence drug distribution? Answer: The first-pass effect reduces the concentration of a drug before it reaches systemic circulation, significantly affecting its overall bioavailability.
Ready to boost your understanding of Drug Absorption and Distribution? Dive into our practice MCQs and test your knowledge to excel in your exams!
Q. What is the effect of protein binding on drug distribution?
A.
Increases free drug concentration
B.
Decreases free drug concentration
C.
Has no effect on drug distribution
D.
Increases drug metabolism
Solution
Protein binding decreases the free drug concentration available for distribution, as only unbound drugs can exert pharmacological effects.
Correct Answer:
B
— Decreases free drug concentration
Q. What is the primary barrier to drug absorption in the gastrointestinal tract?
A.
Mucosal layer
B.
Epithelial cells
C.
Blood-brain barrier
D.
Liver metabolism
Solution
The primary barrier to drug absorption in the gastrointestinal tract is the epithelial cells that line the gut, which must be crossed for absorption to occur.
Q. What is the primary route of drug absorption in the gastrointestinal tract?
A.
Passive diffusion
B.
Facilitated diffusion
C.
Active transport
D.
Endocytosis
Solution
Drugs are primarily absorbed in the gastrointestinal tract through passive diffusion, which allows for the movement of drugs from an area of higher concentration to an area of lower concentration.
