Nitrogen Metabolism

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Q. What condition results from a deficiency in the enzyme ornithine transcarbamylase?
  • A. Phenylketonuria
  • B. Urea cycle disorder
  • C. Maple syrup urine disease
  • D. Homocystinuria
Q. What is the end product of the urea cycle?
  • A. Uric acid
  • B. Ammonia
  • C. Urea
  • D. Creatinine
Q. What is the primary organ responsible for nitrogen metabolism in the human body?
  • A. Liver
  • B. Kidney
  • C. Lungs
  • D. Spleen
Q. What is the primary source of nitrogen for the synthesis of non-essential amino acids?
  • A. Dietary proteins
  • B. Ammonia
  • C. Urea
  • D. Nucleic acids
Q. What is the role of glutamine in nitrogen metabolism?
  • A. Energy source
  • B. Nitrogen donor
  • C. Carbon source
  • D. Hormone precursor
Q. Which amino acid is considered the main nitrogen donor in transamination reactions?
  • A. Glutamate
  • B. Alanine
  • C. Aspartate
  • D. Serine
Q. Which enzyme catalyzes the first step of the urea cycle?
  • A. Carbamoyl phosphate synthetase
  • B. Ornithine transcarbamylase
  • C. Arginase
  • D. Argininosuccinate synthetase
Q. Which metabolic pathway is primarily responsible for the detoxification of ammonia in the liver?
  • A. Glycolysis
  • B. Urea cycle
  • C. Krebs cycle
  • D. Fatty acid oxidation
Q. Which of the following is a key intermediate in the urea cycle?
  • A. Fumarate
  • B. Citrulline
  • C. Aspartate
  • D. Glutamine
Q. Which vitamin is essential for the proper functioning of the enzyme that converts homocysteine to methionine?
  • A. Vitamin B6
  • B. Vitamin B12
  • C. Vitamin C
  • D. Folate
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