Q. What is produced during the decarboxylation of isocitrate?
-
A.
NADH and CO2
-
B.
FADH2 and CO2
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C.
ATP and CO2
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D.
GTP and CO2
Solution
The decarboxylation of isocitrate produces NADH and CO2.
Correct Answer:
A
— NADH and CO2
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Q. What is the primary function of the TCA cycle?
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A.
Fatty acid synthesis
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B.
Amino acid degradation
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C.
Energy production through oxidation of acetyl-CoA
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D.
Nucleotide synthesis
Solution
The TCA cycle primarily functions in the oxidation of acetyl-CoA to produce energy in the form of ATP.
Correct Answer:
C
— Energy production through oxidation of acetyl-CoA
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Q. What role does NAD+ play in the TCA cycle?
-
A.
It acts as a substrate
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B.
It is a coenzyme that accepts electrons
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C.
It is produced during the cycle
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D.
It inhibits the cycle
Solution
NAD+ acts as a coenzyme that accepts electrons during the oxidation reactions in the TCA cycle.
Correct Answer:
B
— It is a coenzyme that accepts electrons
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Q. Which compound is regenerated at the end of the TCA cycle?
-
A.
Acetyl-CoA
-
B.
Citrate
-
C.
Oxaloacetate
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D.
Alpha-ketoglutarate
Solution
Oxaloacetate is regenerated at the end of the TCA cycle, allowing the cycle to continue.
Correct Answer:
C
— Oxaloacetate
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Q. Which enzyme catalyzes the conversion of citrate to isocitrate?
-
A.
Citrate synthase
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B.
Aconitase
-
C.
Isocitrate dehydrogenase
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D.
Alpha-ketoglutarate dehydrogenase
Solution
Aconitase catalyzes the conversion of citrate to isocitrate in the TCA cycle.
Correct Answer:
B
— Aconitase
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Q. Which molecule is the starting substrate for the TCA cycle?
-
A.
Pyruvate
-
B.
Acetyl-CoA
-
C.
Oxaloacetate
-
D.
Citrate
Solution
Acetyl-CoA is the starting substrate for the TCA cycle, combining with oxaloacetate to form citrate.
Correct Answer:
B
— Acetyl-CoA
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Q. Which of the following is NOT a product of the TCA cycle?
-
A.
NADH
-
B.
FADH2
-
C.
ATP
-
D.
Glucose
Solution
Glucose is not a product of the TCA cycle; it is a substrate for glycolysis.
Correct Answer:
D
— Glucose
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Q. Which step of the TCA cycle produces FADH2?
-
A.
Conversion of succinate to fumarate
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B.
Conversion of isocitrate to alpha-ketoglutarate
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C.
Conversion of malate to oxaloacetate
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D.
Conversion of citrate to isocitrate
Solution
The conversion of succinate to fumarate produces FADH2 in the TCA cycle.
Correct Answer:
A
— Conversion of succinate to fumarate
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Q. Which vitamin is a precursor for the coenzyme involved in the TCA cycle?
-
A.
Vitamin C
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B.
Vitamin B1
-
C.
Vitamin B2
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D.
Vitamin B3
Solution
Vitamin B2 (riboflavin) is a precursor for FAD, a coenzyme involved in the TCA cycle.
Correct Answer:
C
— Vitamin B2
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