Pathology & Microbiology

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Q. In chronic inflammation, which cell type is predominantly found in the tissue?
  • A. Neutrophils
  • B. Macrophages
  • C. Mast cells
  • D. Basophils
Q. In which type of hypersensitivity reaction is the immune response primarily mediated by IgE antibodies?
  • A. Type I
  • B. Type II
  • C. Type III
  • D. Type IV
Q. What histological feature is commonly associated with high-grade tumors?
  • A. Well-differentiated cells
  • B. Increased mitotic activity
  • C. Presence of necrosis
  • D. All of the above
Q. What is rigor mortis primarily caused by?
  • A. Depletion of ATP
  • B. Bacterial activity
  • C. Dehydration of tissues
  • D. Increased body temperature
Q. What is the effect of alcohol on the metabolism of acetaminophen?
  • A. Increases its metabolism to non-toxic metabolites
  • B. Decreases its metabolism, increasing toxicity
  • C. Increases its metabolism to toxic metabolites
  • D. Has no effect on its metabolism
Q. What is the effect of St. John's Wort on the metabolism of certain drugs?
  • A. Inhibits CYP450 enzymes
  • B. Induces CYP450 enzymes
  • C. Has no effect on drug metabolism
  • D. Inhibits P-glycoprotein
Q. What is the hallmark histopathological feature of granulomatous inflammation?
  • A. Neutrophilic infiltration
  • B. Caseous necrosis
  • C. Lymphocytic infiltration
  • D. Epithelioid cell formation
Q. What is the main laboratory method used to identify Mycobacterium tuberculosis?
  • A. Gram stain
  • B. Acid-fast bacilli stain
  • C. Culture on blood agar
  • D. PCR
Q. What is the mechanism of interaction between statins and grapefruit juice?
  • A. Inhibition of statin absorption
  • B. Inhibition of CYP3A4 metabolism
  • C. Induction of statin metabolism
  • D. Inhibition of LDL receptor activity
Q. What is the most common laboratory method used to identify Mycobacterium tuberculosis?
  • A. Gram stain
  • B. Acid-fast bacilli stain
  • C. Culture on blood agar
  • D. PCR amplification
Q. What is the most common type of lung cancer associated with smoking?
  • A. Adenocarcinoma
  • B. Squamous cell carcinoma
  • C. Small cell carcinoma
  • D. Large cell carcinoma
Q. What is the most common type of lung cancer?
  • A. Small cell lung cancer
  • B. Non-small cell lung cancer
  • C. Mesothelioma
  • D. Lung carcinoid tumor
Q. What is the primary cause of apoptosis?
  • A. Cellular stress
  • B. Infection
  • C. Tissue injury
  • D. Programmed cell death
Q. What is the primary cause of livor mortis?
  • A. Gravity
  • B. Bacterial action
  • C. Dehydration
  • D. Temperature changes
Q. What is the primary cell type found in nervous tissue?
  • A. Neurons
  • B. Adipocytes
  • C. Chondrocytes
  • D. Osteocytes
Q. What is the primary cell type involved in the acute inflammatory response?
  • A. Neutrophils
  • B. Macrophages
  • C. Lymphocytes
  • D. Eosinophils
Q. What is the primary characteristic used to classify tumors as benign or malignant?
  • A. Size of the tumor
  • B. Histological appearance
  • C. Location of the tumor
  • D. Patient's age
Q. What is the primary concern when combining MAO inhibitors with tyramine-rich foods?
  • A. Hypoglycemia
  • B. Hypertensive crisis
  • C. Serotonin syndrome
  • D. Cardiac arrhythmias
Q. What is the primary function of ciliated columnar epithelium found in the respiratory tract?
  • A. Absorption
  • B. Secretion
  • C. Protection
  • D. Movement of mucus
Q. What is the primary histological feature of atherosclerosis?
  • A. Fibrosis
  • B. Lipid accumulation
  • C. Calcification
  • D. Inflammation
Q. What is the primary mechanism by which Staphylococcus aureus causes disease?
  • A. Production of exotoxins
  • B. Invasion of host cells
  • C. Formation of biofilms
  • D. Induction of apoptosis
Q. What is the primary mechanism by which Staphylococcus aureus evades the host immune response?
  • A. Production of exotoxins
  • B. Formation of biofilms
  • C. Capsule formation
  • D. Endotoxin release
Q. What is the primary mechanism of action for warfarin?
  • A. Inhibition of vitamin K epoxide reductase
  • B. Inhibition of thromboxane A2 synthesis
  • C. Activation of antithrombin III
  • D. Inhibition of platelet aggregation
Q. What is the primary mechanism of cell injury in ischemia?
  • A. Oxidative stress
  • B. Reperfusion injury
  • C. ATP depletion
  • D. Inflammation
Q. What is the primary mechanism of tissue repair following injury?
  • A. Apoptosis
  • B. Regeneration
  • C. Fibrosis
  • D. Necrosis
Q. What is the primary method used for the histopathological diagnosis of tumors?
  • A. Immunohistochemistry
  • B. Flow cytometry
  • C. PCR (Polymerase chain reaction)
  • D. Ultrasound imaging
Q. What is the primary mode of transmission for Helicobacter pylori?
  • A. Airborne droplets
  • B. Fecal-oral route
  • C. Vector-borne
  • D. Direct contact
Q. What is the primary mode of transmission for most viruses?
  • A. Direct contact
  • B. Airborne droplets
  • C. Vector-borne
  • D. Fecal-oral route
Q. What is the primary mode of transmission for Neisseria gonorrhoeae?
  • A. Airborne droplets
  • B. Fecal-oral route
  • C. Sexual contact
  • D. Vector-borne transmission
Q. What is the primary postmortem change that occurs within the first few hours after death?
  • A. Rigor mortis
  • B. Livor mortis
  • C. Algor mortis
  • D. Decomposition
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