Q. Which drug class is commonly used as a first-line treatment for type 2 diabetes?
A.
Sulfonylureas
B.
Biguanides
C.
Thiazolidinediones
D.
Insulin
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Solution
Biguanides, particularly metformin, are commonly used as first-line treatment for type 2 diabetes.
Correct Answer:
B
— Biguanides
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Q. Which drug class is known to have a significant interaction with digoxin, increasing its toxicity?
A.
Beta-blockers
B.
Calcium channel blockers
C.
Macrolide antibiotics
D.
Diuretics
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Solution
Macrolide antibiotics can increase digoxin levels by inhibiting its renal clearance, leading to potential toxicity.
Correct Answer:
C
— Macrolide antibiotics
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Q. Which electrolyte is most important for muscle contraction?
A.
Sodium
B.
Potassium
C.
Calcium
D.
Magnesium
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Solution
Calcium is crucial for muscle contraction as it interacts with proteins in muscle cells to enable contraction.
Correct Answer:
C
— Calcium
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Q. Which electrolyte is primarily regulated by the kidneys?
A.
Calcium
B.
Sodium
C.
Chloride
D.
Magnesium
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Solution
The kidneys play a crucial role in regulating sodium levels in the body, which is vital for fluid balance and blood pressure.
Correct Answer:
B
— Sodium
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Q. Which embryonic structure eventually develops into the spinal cord?
A.
Notochord
B.
Neural tube
C.
Somites
D.
Lateral plate
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Solution
The neural tube develops into the spinal cord and brain.
Correct Answer:
B
— Neural tube
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Q. Which Enterobacteriaceae is known for causing urinary tract infections?
A.
Salmonella enterica
B.
Klebsiella pneumoniae
C.
Shigella dysenteriae
D.
Yersinia pestis
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Solution
Klebsiella pneumoniae is commonly associated with urinary tract infections.
Correct Answer:
B
— Klebsiella pneumoniae
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Q. Which enzyme catalyzes the conversion of citrate to isocitrate?
A.
Citrate synthase
B.
Aconitase
C.
Isocitrate dehydrogenase
D.
Alpha-ketoglutarate dehydrogenase
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Solution
Aconitase catalyzes the conversion of citrate to isocitrate in the TCA cycle.
Correct Answer:
B
— Aconitase
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Q. Which enzyme catalyzes the conversion of glucose to glucose-6-phosphate in glycolysis?
A.
Hexokinase
B.
Phosphofructokinase
C.
Pyruvate kinase
D.
Aldolase
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Solution
Hexokinase catalyzes the phosphorylation of glucose to glucose-6-phosphate.
Correct Answer:
A
— Hexokinase
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Q. Which enzyme catalyzes the first step of the urea cycle?
A.
Carbamoyl phosphate synthetase
B.
Ornithine transcarbamylase
C.
Arginase
D.
Argininosuccinate synthetase
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Solution
Carbamoyl phosphate synthetase catalyzes the first step of the urea cycle, converting ammonia and bicarbonate to carbamoyl phosphate.
Correct Answer:
A
— Carbamoyl phosphate synthetase
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Q. Which enzyme initiates the process of fatty acid oxidation?
A.
Acetyl-CoA carboxylase
B.
Carnitine acyltransferase
C.
Fatty acyl-CoA synthetase
D.
Beta-hydroxyacyl-CoA dehydrogenase
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Solution
Fatty acyl-CoA synthetase initiates fatty acid oxidation by converting fatty acids into fatty acyl-CoA.
Correct Answer:
C
— Fatty acyl-CoA synthetase
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Q. Which enzyme is commonly used in the treatment of pancreatitis?
A.
Amylase
B.
Lipase
C.
Trypsin
D.
Chymotrypsin
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Solution
Lipase is often used in the treatment of pancreatitis to help digest fats when the pancreas is not functioning properly.
Correct Answer:
B
— Lipase
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Q. Which enzyme is commonly used to cut DNA at specific sequences in recombinant DNA technology?
A.
DNA polymerase
B.
Ligase
C.
Restriction endonuclease
D.
Helicase
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Solution
Restriction endonucleases are enzymes that cut DNA at specific sequences, which is essential for recombinant DNA technology.
Correct Answer:
C
— Restriction endonuclease
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Q. Which enzyme is commonly used to insert DNA fragments into cloning vectors?
A.
Ligase
B.
Polymerase
C.
Restriction enzyme
D.
Helicase
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Solution
DNA ligase is commonly used to insert DNA fragments into cloning vectors by joining the DNA ends.
Correct Answer:
A
— Ligase
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Q. Which enzyme is crucial for converting starches into fermentable sugars in ethanol production?
A.
Amylase
B.
Cellulase
C.
Protease
D.
Lipase
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Solution
Amylase is crucial for converting starches into fermentable sugars during the ethanol production process.
Correct Answer:
A
— Amylase
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Q. Which enzyme is crucial for the conversion of pyruvate to acetyl-CoA?
A.
Lactate dehydrogenase
B.
Pyruvate kinase
C.
Pyruvate dehydrogenase
D.
Alcohol dehydrogenase
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Solution
Pyruvate dehydrogenase is the enzyme that converts pyruvate to acetyl-CoA.
Correct Answer:
C
— Pyruvate dehydrogenase
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Q. Which enzyme is involved in the digestion of carbohydrates?
A.
Pepsin
B.
Amylase
C.
Lipase
D.
Trypsin
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Solution
Amylase is the enzyme that breaks down carbohydrates into simpler sugars.
Correct Answer:
B
— Amylase
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Q. Which enzyme is responsible for breaking down hydrogen peroxide in cells?
A.
Catalase
B.
Amylase
C.
Lipase
D.
Protease
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Solution
Catalase is the enzyme that catalyzes the decomposition of hydrogen peroxide into water and oxygen.
Correct Answer:
A
— Catalase
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Q. Which enzyme is responsible for breaking down lactose into glucose and galactose?
A.
Amylase
B.
Lactase
C.
Protease
D.
Lipase
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Solution
Lactase is the enzyme that catalyzes the hydrolysis of lactose into glucose and galactose.
Correct Answer:
B
— Lactase
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Q. Which enzyme is responsible for synthesizing RNA from a DNA template?
A.
DNA polymerase
B.
RNA polymerase
C.
Ribosome
D.
Ligase
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Solution
RNA polymerase is the enzyme that synthesizes RNA by transcribing the DNA template during the process of transcription.
Correct Answer:
B
— RNA polymerase
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Q. Which enzyme is responsible for the breakdown of carbohydrates in the mouth?
A.
Pepsin
B.
Amylase
C.
Lipase
D.
Trypsin
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Solution
Salivary amylase is the enzyme that begins the breakdown of carbohydrates in the mouth.
Correct Answer:
B
— Amylase
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Q. Which enzyme is responsible for the hydrolysis of lactose in E. coli?
A.
Lactase
B.
Beta-galactosidase
C.
Lactose permease
D.
Galactosidase
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Solution
Beta-galactosidase is the enzyme that hydrolyzes lactose into glucose and galactose in E. coli.
Correct Answer:
B
— Beta-galactosidase
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Q. Which enzyme is responsible for the unwinding of DNA during replication?
A.
DNA polymerase
B.
Helicase
C.
Ligase
D.
Primase
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Solution
Helicase is the enzyme that unwinds the DNA double helix, allowing replication to occur.
Correct Answer:
B
— Helicase
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Q. Which factor can affect enzyme activity?
A.
Temperature
B.
pH
C.
Substrate concentration
D.
All of the above
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Solution
Enzyme activity can be affected by temperature, pH, and substrate concentration, making all of these factors important.
Correct Answer:
D
— All of the above
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Q. Which factor can affect the resolution in HPLC?
A.
Column length
B.
Particle size of stationary phase
C.
Flow rate
D.
All of the above
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Solution
All of the above factors can affect the resolution in HPLC, influencing the separation quality of analytes.
Correct Answer:
D
— All of the above
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Q. Which factor can affect the resolution of a gas chromatography separation?
A.
Column length
B.
Temperature of the detector
C.
Type of carrier gas
D.
All of the above
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Solution
All of the above factors can affect the resolution of a gas chromatography separation.
Correct Answer:
D
— All of the above
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Q. Which factor can affect the yield of protein purification?
A.
Temperature
B.
pH
C.
Choice of purification method
D.
All of the above
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Solution
All of the above factors can significantly affect the yield of protein purification.
Correct Answer:
D
— All of the above
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Q. Which factor does NOT affect enzyme activity?
A.
Temperature
B.
pH
C.
Substrate concentration
D.
Color of the enzyme
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Solution
The color of the enzyme does not affect its activity; however, temperature, pH, and substrate concentration do.
Correct Answer:
D
— Color of the enzyme
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Q. Which factor does NOT affect the separation in chromatography?
A.
Temperature
B.
Flow rate of the mobile phase
C.
Nature of the stationary phase
D.
Color of the sample
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Solution
The color of the sample does not affect the separation in chromatography.
Correct Answer:
D
— Color of the sample
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Q. Which factor does NOT affect the viscosity of blood?
A.
Temperature
B.
Hematocrit level
C.
Blood vessel length
D.
Plasma protein concentration
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Solution
Blood vessel length does not affect the viscosity of blood; viscosity is influenced by temperature, hematocrit level, and plasma protein concentration.
Correct Answer:
C
— Blood vessel length
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Q. Which factor does NOT significantly affect drug absorption?
A.
pH of the environment
B.
Surface area of absorption
C.
Molecular weight of the drug
D.
Color of the drug
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Solution
The color of the drug does not significantly affect drug absorption, while pH, surface area, and molecular weight are critical factors.
Correct Answer:
D
— Color of the drug
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